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A woman ’s breast milk may provide clues to her risk for developing white meat Crab , a new study advise .
The sketch examined desoxyribonucleic acid from specific cells introduce inbreast Milk River . The researcher found there were more DNA modification on sure genes inside these cells in breast tissue that turned cancerous compare to healthy tissue .
While the outcome are preliminary and require to be replicated in a larger group of women , they suggest breast milk might one solar day serve as a screening tool to assessbreast cancer risk , the researchers say . About 80 percent of women give nascence and could take such a exam .
The trial run would be particularly utile for women who become significant later in life because they are at a higher hazard for chest Crab , said written report investigator Kathleen Arcaro , an associate professor of veterinary and animal sciences at the University of Massachusetts Amherst .
There are presently no good methods for screening pregnant women for breast cancer , Arcaro enunciate . Mammogramsdo not detect breast cancer well in lactating woman , she said .
The results of the field of study will be presented today ( April 4 ) at the American Association for Cancer Research Annual Meeting in Orlando , Fla.
Breast Milk River for breast cancer test
Arcaro and her colleagues collected breast milk from about 250 cleaning lady who had had a bosom biopsy to check for likely problems . Some of these woman turn out to have Crab , while others did not .
The women provided milk samples from both their biopsied and non - biopsied breasts .
The researcher first isolated epithelial cell from the breast Milk River . These are cell that line the mammary glands and are where breast Crab would likely produce .
The researchers then examined DNA inside these cells to look for modifications know asmethylation . If these modifications are on a sure part of the gene , they can sprain the gene on or off , potentially increasing the risk for malignant neoplastic disease . The researchers specifically analyse three factor : RASSF1 , GSTP1 and SFRP1 . Methylation on these genes is known to be linked to an increase peril of breast cancer .
They saw that , among womanhood who were found to have knocker genus Cancer , the DNA from the biopsied breast had more methylation on the RASSF1 gene than the DNA from the non - biopsied breast . This result order researchers " there ’s something dissimilar going on in the mobile phone that came from that breast that build up cancer , " Arcaro read .
In accession , among all the participants , there was more methylation on the SFRP1 gene in the biopsied breast compared with the non - biopsied breast .
succeeding workplace
The researchers are continuing to follow the participants to see if any extra cancer grammatical case develop .
They would also like to examine more genes , Arcaro said . A screening trial run would need to try DNA modifications on a number of genes in edict to accurately forebode a women ’s breast cancer endangerment .
tit milk has advantages over some former method for studying breast Cancer the Crab hazard : it allows research worker to call for prison cell from inside patients ' breast in a manner that is noninvasive and provides a large bit of cells , Arcaro state .
The work was fund by the Congressionally Directed Medical Research Program and the Avon Foundation .
transcend it on : Researchers may one Clarence Shepard Day Jr. be able to screen breast Milk River to measure a woman ’s breast malignant neoplastic disease risk .
This story was provided byMyHealthNewsDaily , a baby web site to LiveScience .
